IL-10 related inflammatory bowel disease


Description

Loss-of-function mutations in IL10, IL10RA and IL10RB are associated with hyper-inflammatory immune responses in the intestine resulting in severe, infantile-onset inflammatory bowel disease


Request a test

When requesting this test please use the referral form provided and complete the required proforma. No testing will be carried out without a proforma.


Additional information

For additional information please click on the link Download additional information >


Sending address

Great Ormond Street Hospital NE Thames Regional Genetics Service Laboratories
Great Ormond Street Hospital for Children
Barclay House
37 Queen Square
London
WC1N 3BH

Laboratory service

Genetics


Sample requirements

1ml EDTA neonates, 5ml EDTA adults


Reference range

Not applicable


Disease / group

IL10; IL10RA; IL10RB


Cost

Upon request


Call in advance?

Prenatals must be arranged in advance, through a Clinical Genetics department if possible.


Genetics

The Genetics Laboratories provide an extensive range of Cytogenetics and Molecular Genetics diagnostic testing services.

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