IL-10 related inflammatory bowel disease


Description

Loss-of-function mutations in IL10, IL10RA and IL10RB are associated with hyper-inflammatory immune responses in the intestine resulting in severe, infantile-onset inflammatory bowel disease


Request a test

When requesting this test please use the referral form provided and complete the required proforma. No testing will be carried out without a proforma.


Additional information

For additional information please click on the link


Sending address

Rare & Inherited Disease Laboratory
London North Genomic Laboratory Hub
Great Ormond Street Hospital for Children
Levels 4-6 Barclay House
37 Queen Square
London
WC1N 3BH

Laboratory service

Genetics


Sample requirements

1ml EDTA neonates, 5ml EDTA adults


Reference range

Not applicable


Disease / group

IL10; IL10RA; IL10RB


Cost

Upon request


Call in advance?

Prenatals must be arranged in advance, through a Clinical Genetics department if possible.


Genetics

The Genetics Laboratories provide an extensive range of Cytogenetics and Molecular Genetics diagnostic testing services.

© 2011 Great Ormond Street Hospital for Children NHS Trust