The X-inactivation status of females may be determined using X-linked methylation sensitive polymorphic markers. This information may be useful to explain the manifestation of X-linked recessive conditions in females or to indicate carrier status for certain X-linked disorders

Request a test

When requesting this test please use the referral form provided. Please also refer to any additional information provided for this test.

Additional information

For additional information please click on the link

Sending address

Rare & Inherited Disease Laboratory
London North Genomic Laboratory Hub
Great Ormond Street Hospital for Children
Levels 4-6 Barclay House
37 Queen Square

Laboratory service


Sample requirements

5 ml EDTA. Certain immunodeficiency sydromes require separated B or T cells - please see information sheet for details.

Reference range

Not applicable

Turnaround time

20 days


Upon request

Call in advance?

Not required


The Genetics Laboratories provide an extensive range of Cytogenetics and Molecular Genetics diagnostic testing services.

© 2011 Great Ormond Street Hospital for Children NHS Trust