Cytomegalovirus PCR


Description

CMV causes mild or subclinical infection in the immunocompetent host. This real-time, quantitative polymerase chain reaction (PCR) assay is used for the regular screening of immunocompromised patients, such as those undergoing bone marrow or solid organ transplants; the early detection of CMV viraemia can allow pre-emptive antiviral therapy. Additionally, the quantitative nature of this assay allows viral load to be monitored during treatment and thus may indicate the presence of antiviral resistant infection, as well as successful treatment. This assay is also used for the detection of congenital CMV infection, often by detection of CMV in urine, as well as respiratory tract infection, hepatitis, colitis, encephalitis and retinitis. The assay includes an internal control for control of both the nucleic extraction and amplification processes.

Also known as

CMV PCR


Request a test

To request this test please send sample with a request providing patient ID (three identifiers), specimen information, assay required, relevant clinical details and sender information. Before sending sample please read details on requesting and labelling by clicking on the link. Please also refer to any additional information provided for this test. Download the referral form >


Additional information

This assay is duplexed with Adenovirus PCR


Sending address

Microbiology, Virology and Infection Control Level 4, Camelia Botnar Laboratories Great Ormond Street Hospital for Children Great Ormond Street London WC1N 3JH DX number: DX6640203 DX Exchange: Bloomsbury 91WC

Laboratory service

Microbiology, Virology and Infection Control


Sample requirements

Sterile container containing any of the following, as appropriate: EDTA whole blood or plasma (2ml in appropriate blood tube), serum (5ml in clotted blood tube), urine (1ml), NPA, BAL, biopsy of any relevant organ, CSF (minimum 200ul)


Reference range

Not applicable


Turnaround time

24 hours


Disease / group

Viral infection


Cost

Upon request


Call in advance?

Not required


Microbiology, Virology and Infection Control

Our laboratory performs a wide range of routine and specialist investigations in Bacteriology, Virology and PCR.

© 2011 Great Ormond Street Hospital for Children NHS Trust