Pre-bone marrow transplant serology screen


Description

Patients undergoing bone marrow transplant (with the exception of those with severe combined immunodeficiency), and their donor, are subject to a pre-transplant serology assessment. A combination of automated detection by ELFA and manual EIA is used for the detection of Toxoplasma gondii total antibody, as well as VZV, measles, CMV, rubella, HSV and EBV VCA IgG. The immune status of the patient to each organism is therefore determined; the potential for primary infection, re-infection or reactivation when immunosuppressed is thus known and, where possible, recipients and donors are matched according to their CMV and EBV serostatus. The pre-transplant assessment also includes blood borne virus screening by ELFA or EIA for anti-HIV antibodies and p24 antigen, Hepatitis B surface antigen and Hepatitis C antibody and core antigen.

Also known as

Pre-BMT assessment


Request a test

To request this test please send sample with a request providing patient ID (three identifiers), specimen information, assay required, relevant clinical details and sender information. Before sending sample please read details on requesting and labelling by clicking on the link. Please also refer to any additional information provided for this test. Download the referral form >


Additional information

Individual tests from the screen can also be requested, as appropriate


Sending address

Microbiology, Virology and Infection Control Level 4, Camelia Botnar Laboratories Great Ormond Street Hospital for Children Great Ormond Street London WC1N 3JH DX number: DX6640203 DX Exchange: Bloomsbury 91WC

Laboratory service

Microbiology, Virology and Infection Control


Sample requirements

Serum (10ml in clotted blood tube)


Reference range

Not applicable


Turnaround time

Automated results within 24 hours, manual results within 7 days


Disease / group

Viral infection, viral immunity


Cost

Upon request


Call in advance?

Not required


Microbiology, Virology and Infection Control

Our laboratory performs a wide range of routine and specialist investigations in Bacteriology, Virology and PCR.

© 2011 Great Ormond Street Hospital for Children NHS Trust