Newborn Screening

GOSH Newborn Screening Laboratory is the largest Newborn Screening laboratory in the UK, covering maternity units in North London, Hertfordshire, Bedfordshire and Essex. Approximately 125 000 newborns are screened at GOSH every year and this accounts for approximately one in every six babies born in England.


Screening is offered for the following conditions:

-        Phenylketonuria

-        Congenital Hypothyroidism

-        Cystic Fibrosis

-        MCADD

-        Sickle Cell Disease

-        Maple Syrup Urine Disease

-        Homocystinuria (pyridoxine unresponsive)

-        Glutaric aciduria type 1

-        Isovaleric acidaemia


The Newborn Screening Laboratory works in conjunction with other laboratories in the screening pathway:

-        Haemoglobinopathy Screening Laboratory, Central Middlesex Hospital

-        Molecular Genetics Laboratory, Kennedy Galton Centre, Northwick Park Hospital

-        Molecular Genetics Laboratory, Kings College Hospital

-        SE Thames Newborn Screening laboratory, Viapath, St Thomas Hospital


We have close links to clinical teams for the referral of positive cases.


Opening Hours


9am to 5:30pm Mon to Fri


Contact details


Telephone : 0207 405 9200 ext 8383/8251


Fax: 0207 829 8801


Email: or


© 2011 Great Ormond Street Hospital for Children NHS Trust