Translocation Detection by Reverse transcriptase polymerase chain reaction (RT-PCR). All tests are comlemented by amplification of a relevant housekeeping gene to test the quality of the RNA.Please note that this test is currently not quantitative.

Request a test

When requesting this test please use the referral form provided. Please also refer to any additional information provided for this test. Download the referral form >

Additional information

The BCR-ABL p210 transcript is observed in nearly all cases of CML. Philadelphia positive ALL cases are associated with the BCR-ABL p190 transcript as well as a number of CMML cases. The RT-PCR test is currently qualitative.

Sending address

Paediatric Malignancy Unit Great Ormond Street Hospital for Sick Children Level 2, Camelia Botnar Laboratories Great Ormond Street London WC1N 3JH

Laboratory service

Paediatric Malignancy Unit

Sample requirements

5 mls EDTA blood or bone marrow. Please ensure the sample arrives as soon as possible after being taken.

Reference range

Not applicable

Turnaround time

3-5 working days

Disease / group

Chronic Myeloid leukemia


Upon request

Call in advance?

Please call in advance to discuss requirements

Paediatric Malignancy Unit

The Paediatric Malignancy Unit is a unit providing a wide range of molecular genetic and cytogenetic diagnostic tests.

© 2011 Great Ormond Street Hospital for Children NHS Trust